

SkinCeuticals Discoloration Defense
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Discoloration Defense is a layerable, daily-use dark spot corrector clinically proven to reduce the appearance of key types of skin discoloration, including hard-to-treat forms such as stubborn brown patches and post-acne marks. Formulated with 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES, this latest-generation formula improves the appearance of skin discoloration, brightens skin, and evens skin tone in as early as 2 weeks.
Clinical Studies:
In a 12-week clinical study*, Discoloration Defense significantly improved the appearance of key skin discoloration markers:
- 60% average improvement in the appearance of stubborn brown patches
- 59% average improvement in the appearance of skin discoloration
- 81% average improvement in the appearance of post-acne marks
- 59% average improvement in the appearance of even skin tone
*A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild-to-moderate facial skin discoloration, including stubborn dark spots, post-acne marks and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.